Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 5/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693263 | 0.85 | NPSR1 (0.46) | NR3C1ARNPSR1LMNAKDM4E | |
| SCHEMBL8688576 | 0.78 | PTGS1 (0.49) | NPSR1LMNAALDH1A1GAAHPGD | |
| SCHEMBL8639075 | 0.76 | PTGS2 (0.41) | NR3C1ARNPSR1LMNAALDH1A1 | |
| SCHEMBL8638994 | 0.75 | LMNA (0.46) | NPSR1LMNAKDM4EALDH1A1GAA | |
| SCHEMBL8688508 | 0.75 | PTGS1 (0.49) | NPSR1LMNAKDM4EALDH1A1GAA | |
| SCHEMBL8639252 | 0.74 | LMNA (0.48) | NPSR1LMNAKDM4EALDH1A1GAA | |
| SCHEMBL8351386 | 0.74 | PTGS2 (0.49) | NR3C1AR | |
| SCHEMBL8689251 | 0.72 | ALDH1A1 (0.42) | NPSR1LMNAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8691849 | 0.72 | PTGS2 (0.49) | NPSR1KDM4EALDH1A1HPGDFFAR4 | |
| SCHEMBL8638976 | 0.72 | PTGS2 (0.37) | NR3C1NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753688-A | ANTIINFLAMMATORY | TALLEY JOHN J (US) | 1998-05-19 | — | — | US | disclosed |
| US-5510496-A | ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1996-04-23 | — | — | US | disclosed |
| US-5504215-A | Substituted pyrazolyl benzenesulfonamide compounds for the treatment of inflammation | G. D. SEARLE & CO. (US) | 1996-04-02 | — | — | US | disclosed |