Water

Water

SCHEMBL863777

O.[Rh]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL7205424 1.00
Water SCHEMBL28081725 1.00
Water SCHEMBL161891 1.00
Water SCHEMBL27943878 1.00
Water SCHEMBL7646361 1.00
Iodide SCHEMBL811216 0.82
Hydrochloric Acid SCHEMBL8911044 0.82 CA4 (0.33)
Hydrochloric Acid SCHEMBL441937 0.82
Bromide SCHEMBL7857756 0.82
Water SCHEMBL3152279 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 899 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120158615-A Method for separating platinum and rhodium with high direct yield 紫金铜业有限公司 2025-06-17 CN claimed
CN-120081782-A Preparation method of 2-aminoethyl-3-chloro-5-trifluoromethylpyridine 天津均凯农业科技有限公司 2025-06-03 CN claimed
CN-120037987-A Aryl phosphine oxide ligand copper-based catalyst, preparation method thereof and application thereof in hydrochlorination of acetylene 贵州重力科技环保股份有限公司 2025-05-27 CN claimed
CN-118126096-B Endoplasmic reticulum targeted rhodium (I) complex, preparation method and application 南华大学 2025-04-15 CN claimed
US-12269016-B2 Rhodium-containing layered catalyst structures and methods of making the same GM Global Technology Operations LLC (US) 2025-04-08 US claimed
CN-119706983-A Rhodium nitrate crystal preparation method based on rhodium-containing waste liquid 浙江微通催化新材料有限公司 2025-03-28 CN claimed
CN-115849586-B Method for recovering rhodium from rhodium-containing wastewater and recovered rhodium salt 中国石油化工股份有限公司 2025-03-28 CN claimed
CN-119637966-A Method for preparing soluble rhodium compound 陕西宝成航空仪表有限责任公司 2025-03-18 CN claimed
CN-119566029-A High rhodium aqua regia slag reduction recovery device 太原华盛丰贵金属材料有限公司 2025-03-07 CN claimed
CN-119332092-A Method and device for recovering rhodium in low-content rhodium liquid 昆山鸿福泰环保科技有限公司 2025-01-21 CN claimed
US-4444898-A Heterocatalyst system UNIVERSITY PATENTS, INC. (US) 1984-04-24 US claimed
US-4433901-A All solid type electrochromic display element NIPPON KOGAKU K.K. (JP) 1984-02-28 US claimed
EP-0098289-A1 HETEROCATALYST SYSTEM UNIVERSITY PATENTS, INC. (US) 1984-01-18 EP claimed
US-4420420-A OXIDATION, HYDROGENATION CATALYST SHOWA DENKO KABUSHIKI KAISHA (JP) 1983-12-13 US claimed
WO-1983002404-A1 HETEROCATALYST SYSTEM UNIVERSITY PATENTS INC (US) 1983-07-21 WO claimed
US-4389348-A Selective hydrogenation of dinitrile to omega-aminonitrile and supported rhodium-containing catalyst therefor ALLIED CORPORATION (US) 1983-06-21 US claimed
EP-0077911-A1 Selective hydrogenation of dinitriles to omega-aminonitriles ALLIED CORPORATION (US) 1983-05-04 EP claimed
US-4376724-A REDUCTION, CATALYST SUPPORTS SHOWA DENKO KABUSHIKI KAISHA (JP) 1983-03-15 US claimed
US-3947458-A RHODIUM CATALYST, REACTING NITROGEN COMPOUND, OLEFIN, CARBON MONOXIDE, WATER MONSANTO COMPANY (US) 1976-03-30 US claimed
US-3944615-A TERTIARY AMINE OR AMIDE AND A RHODIUM CONTAINING CATALYST MONSANTO COMPANY (US) 1976-03-16 US claimed