Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 3/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PKLR | P30613 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6902980 | 0.76 | MAPK8 (0.45) | MAPK8MAPK9MAPK10MEN1KMT2A | |
| SCHEMBL29456254 | 0.76 | MAPK8 (0.45) | MAPK8MAPK9MAPK10MEN1KMT2A | |
| SCHEMBL19386402 | 0.76 | MAPT (0.44) | MAPK8MAPK9MAPK10MEN1KMT2A | |
| SCHEMBL3713718 | 0.71 | KDM4E (0.50) | MAPK8MAPK9MAPK10MEN1KMT2A | |
| SCHEMBL8637806 | 0.70 | MAPT (0.37) | MEN1KMT2AALDH1A1ADAM17MAPT | |
| SCHEMBL8596016 | 0.70 | MAPT (0.48) | MAPK8MAPK9MAPK10MEN1KMT2A | |
| SCHEMBL3709497 | 0.69 | MAPK8 (0.46) | MAPK8MAPK9MAPK10MEN1KMT2A | |
| SCHEMBL25846851 | 0.67 | LOXL2 (0.52) | MAPK8MAPK9MAPK10MEN1KMT2A | |
| SCHEMBL10052953 | 0.67 | KDM4E (0.39) | MAPK8MAPK9MAPK10MEN1KMT2A | |
| SCHEMBL8637798 | 0.66 | MAPT (0.49) | MEN1KMT2AALDH1A1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |