Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.31 |
| ▸ | TUBB | P07437 | 2/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.31 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.31 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.31 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.31 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29420719 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C | |
| SCHEMBL218213 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C | |
| SCHEMBL381604 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C | |
| SCHEMBL8855966 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C | |
| SCHEMBL25218345 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C | |
| SCHEMBL31325259 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C | |
| SCHEMBL7452092 | 0.77 | ALDH1A1 (0.44) | SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C | |
| SCHEMBL5734495 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C | |
| SCHEMBL7831181 | 0.77 | NISCH (0.44) | SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C | |
| SCHEMBL31048511 | 0.77 | NISCH (0.44) | SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723667-A | Method of producing optically active tert-leucinol and its use | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1998-03-03 | — | — | US | claimed |
| EP-0728736-A1 | Process for the preparation of optically active tert-leucinol and use thereof | Degussa Aktiengesellschaft (DE) | 1996-08-28 | — | — | EP | claimed |
| EP-0728736-B1 | Process for the preparation of optically active tert-leucinol and use thereof | DEGUSSA (DE) | 1998-08-19 | — | — | EP | disclosed |
| US-5723667-A | Method of producing optically active tert-leucinol and its use | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1998-03-03 | — | — | US | disclosed |
| EP-0728736-A1 | Process for the preparation of optically active tert-leucinol and use thereof | Degussa Aktiengesellschaft (DE) | 1996-08-28 | — | — | EP | disclosed |