Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | C1R | P00736 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | KLK1 | P06870 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | C1S | P09871 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.31 |
| ▸ | TUBB | P07437 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25211097 | 0.89 | SMN1; SMN2 (0.36) | SMN1; SMN2ADRA2AADRA2BADRA2CMMP12 | |
| SCHEMBL29420719 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C | |
| SCHEMBL218213 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C | |
| SCHEMBL18953860 | 0.84 | SMN1; SMN2 (0.38) | SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C | |
| SCHEMBL381604 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C | |
| SCHEMBL8855966 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C | |
| SCHEMBL8638335 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C | |
| SCHEMBL5734495 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C | |
| SCHEMBL7452092 | 0.77 | ALDH1A1 (0.44) | SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C | |
| SCHEMBL7831181 | 0.77 | NISCH (0.44) | SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185571-B1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIV OF KWAZULU NATAL (ZA) | 2026-05-20 | — | — | EP | claimed |
| US-12441721-B2 | Synthesis of heterocyclic compounds from carboxamide and carboxamide derivatives with haloalkanols | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2025-10-14 | — | — | US | claimed |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2023-09-21 | — | — | US | claimed |
| EP-4185571-A2 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | University Of Kwazulu-Natal (ZA) | 2023-05-31 | — | — | EP | claimed |
| EP-4185571-B1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIV OF KWAZULU NATAL (ZA) | 2026-05-20 | — | — | EP | disclosed |
| US-12441721-B2 | Synthesis of heterocyclic compounds from carboxamide and carboxamide derivatives with haloalkanols | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2025-10-14 | — | — | US | disclosed |
| EP-4556468-A2 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | University of KwaZulu-Natal (ZA) | 2025-05-21 | — | — | EP | disclosed |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2023-09-21 | — | — | US | disclosed |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2023-09-21 | — | — | US | disclosed |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2023-09-21 | — | — | US | disclosed |
| EP-4185571-A2 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | University Of Kwazulu-Natal (ZA) | 2023-05-31 | — | — | EP | disclosed |
| CN-113135869-B | Method for preparing alpha-aryl carbonyl compound and product | 浙江师范大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-113135869-A | Method for preparing alpha-aryl carbonyl compound and product | 浙江师范大学 | 2021-07-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12441721-B2 | Synthesis of heterocyclic compounds from carboxamide and carboxamide derivatives with haloalkanols | NAAA, CNR2, AADAC | SMN1; SMN2 4831/4885KCNN4 2430/4885ADRA2A 669/4885 |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | NAAA, CNR2, AADAC | SMN1; SMN2 4831/4885KCNN4 2430/4885ADRA2A 669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.