SCHEMBL8634835

SCHEMBL8634835

FC(F)(F)c1ccc(Oc2ccc(OCC=C(Cl)Cl)c(Br)c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.42
SLC6A4 P31645 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.38
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
ATM Q13315 1/20 0.37
PPARD Q03181 3/20 0.37
RAB9A P51151 1/20 0.36
MAOB P27338 1/20 0.36
AOC3 Q16853 1/20 0.36
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36
PDE4D Q08499 1/20 0.36
ALOX5 P09917 1/20 0.36
PPARG P37231 1/20 0.36
PSEN1 P49768 1/20 0.36
FFAR1 O14842 2/20 0.36
PTGDR2 Q9Y5Y4 1/20 0.36
PTPN1 P18031 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8634562 0.88 FFAR1 (0.47) THRBSLC6A4L3MBTL1LMNAMAPT
SCHEMBL8636474 0.86 RXRA (0.38) THRBSLC6A4L3MBTL1LMNAMAPT
SCHEMBL8636502 0.86 SMN1; SMN2 (0.53) LMNAMAPTRAB9AFFAR1
SCHEMBL8632579 0.84 NPC1 (0.38) SLC6A4LMNAMAPTRAB9AMAOB
SCHEMBL8633981 0.81 EPAS1 (0.38) LMNAMAPTRAB9A
SCHEMBL8636720 0.80 ACACB (0.37) THRBLMNAMAPTRAB9A
SCHEMBL8634621 0.80 MAOB (0.37) L3MBTL1LMNAMAPTATMRAB9A
SCHEMBL8080574 0.79 RHOC (0.51) LMNAMAPTPPARDRAB9ACYP1A1
SCHEMBL8638413 0.79 FFAR1 (0.47) THRBSLC6A4L3MBTL1LMNAMAPT
SCHEMBL8633461 0.79 PPARG (0.39) SLC6A4LMNAMAPTPPARDMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed