Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960199 | 0.88 | KDM4E (0.55) | KDM4ESMN1; SMN2CES2MAPTALDH1A1 | |
| Nornitrogen Mustard SCHEMBL8637079 | 0.85 | KMT2A (0.52) | SMN1; SMN2CES2MAPTALDH1A1TDP1 | |
| SCHEMBL2770959 | 0.77 | HPGD (0.46) | KDM4ESMN1; SMN2MAPTALDH1A1TDP1 | |
| SCHEMBL10426166 | 0.76 | ALDH1A1 (0.48) | SMN1; SMN2CES2MAPTALDH1A1TDP1 | |
| SCHEMBL1403472 | 0.76 | ALDH1A1 (0.56) | KDM4ESMN1; SMN2MAPTALDH1A1TDP1 | |
| SCHEMBL30203403 | 0.76 | ALDH1A1 (0.56) | KDM4ESMN1; SMN2MAPTALDH1A1TDP1 | |
| SCHEMBL9502855 | 0.76 | CES2 (0.58) | KDM4ESMN1; SMN2CES2MAPTALDH1A1 | |
| SCHEMBL11130755 | 0.76 | CES2 (0.58) | KDM4ESMN1; SMN2CES2MAPTALDH1A1 | |
| SCHEMBL8637553 | 0.75 | CES2 (0.46) | SMN1; SMN2CES2MAPTALDH1A1FLT1 | |
| SCHEMBL6750268 | 0.75 | SMN1; SMN2 (0.65) | KDM4ESMN1; SMN2CES2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750782-A | ANTICARCINOGENIC AGENTS, ANTIHYPOXIC AGENTS, PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |