SCHEMBL8633096

SCHEMBL8633096

Cc1cc(OCC=C(Cl)Cl)c(Cl)cc1Oc1ccc(OC(C)C)cc1

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.34
PTGDR Q13258 5/20 0.34
FFAR4 Q5NUL3 4/20 0.34
ACACB O00763 3/20 0.33
ACACA Q13085 2/20 0.33
FFAR1 O14842 1/20 0.33
PNLIP P16233 1/20 0.33
CARM1 Q86X55 1/20 0.32
PRMT6 Q96LA8 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CSNK2A1 P68400 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8634698 0.93 HTT (0.37) HTTPTGDRFFAR4ACACBACACA
SCHEMBL8634719 0.89 PTGDR (0.34) PTGDRACACBACACAFFAR1PNLIP
SCHEMBL8633931 0.84 HTT (0.39) HTTPTGDRFFAR4ACACBACACA
SCHEMBL8633666 0.81 MPO (0.36) PTGDRACACBACACAFFAR1TSHR
SCHEMBL8638987 0.81 PPARA (0.36) HTTFFAR4FFAR1
SCHEMBL8635751 0.79 HTT (0.46) HTTACACBFFAR1PNLIP
SCHEMBL8634567 0.77 ADRA2A (0.37) HTTPTGDRFFAR4ACACBACACA
SCHEMBL8635966 0.76 THRB (0.39) HTTPTGDRFFAR4ACACBACACA
SCHEMBL8634858 0.76 HTT (0.39) HTTPTGDRFFAR4ACACBACACA
SCHEMBL8636720 0.76 ACACB (0.37) HTTPTGDRFFAR4ACACBACACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed