SCHEMBL8633455

SCHEMBL8633455

Cc1cc(OCC=C(Br)Br)c(Cl)cc1Oc1ccc(OCC(F)(F)F)cc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 6/20 0.36
PPARD Q03181 5/20 0.34
PPARG P37231 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
LMNA P02545 1/20 0.34
PAX8 Q06710 1/20 0.34
ALDH1A1 P00352 1/20 0.33
FFAR1 O14842 2/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CYP2C9 P11712 2/20 0.32
CYP1A2 P05177 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP17A1 P05093 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8638987 0.90 PPARA (0.36) PPARAPPARDPPARGMEN1KMT2A
SCHEMBL8634719 0.82 PTGDR (0.34) FFAR1
SCHEMBL8633395 0.78 ALDH1A1 (0.39) PPARAPPARDPPARGMEN1KMT2A
SCHEMBL8633759 0.77 PNLIP (0.38) MEN1KMT2AALDH1A1FFAR1MAPT
SCHEMBL8632656 0.75 KDM4E (0.37) MEN1KMT2ALMNAPAX8ALDH1A1
SCHEMBL8636315 0.74 PPARD (0.43) PPARAPPARDLMNAALDH1A1FFAR1
SCHEMBL8633666 0.74 MPO (0.36) FFAR1CYP1A2CYP2C19
SCHEMBL8633527 0.73 LTA4H (0.35) MEN1KMT2ALMNAALDH1A1MAPT
SCHEMBL8637913 0.72 CYP1A2 (0.46) KMT2ALMNAALDH1A1FFAR1MAPT
SCHEMBL8632925 0.72 FFAR1 (0.50) PPARAPPARDMEN1KMT2AFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed