Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.56 |
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
| ▸ | PNMT | P11086 | 2/20 | 0.46 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27908224 | 0.89 | HTR2C (0.59) | HTR2CHTR7IDO1PARP10PARP11 | |
| SCHEMBL1067431 | 0.78 | CHRNB4 (0.50) | HTR2CIDO1CHRNB4CHRNA3TP53 | |
| SCHEMBL8638141 | 0.76 | SIGMAR1 (0.52) | HTR2CHTR7PNMTASIC3HTR2A | |
| SCHEMBL27676378 | 0.76 | PRCP (0.48) | HTR2CHTR7PNMTCYP3A4SIGMAR1 | |
| SCHEMBL8350829 | 0.76 | AHR (0.48) | HTR2CPNMTASIC3HTR2AHTR2B | |
| SCHEMBL27656138 | 0.74 | CHRNB4 (0.56) | HTR2CIDO1CHRNB4CHRNA3MAPT | |
| SCHEMBL8349987 | 0.74 | ASIC3 (0.64) | HTR2CASIC3IDO1PARP10PARP11 | |
| Hydrochloric Acid SCHEMBL7050205 | 0.73 | HTR2C (0.49) | HTR2CHTR7PNMTASIC3PARP10 | |
| SCHEMBL4810826 | 0.72 | CHRNB4 (0.55) | HTR2CIDO1CHRNB4CHRNA3MAPT | |
| SCHEMBL8638170 | 0.72 | MLNR (0.39) | HTR2CPNMTASIC3HTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |