Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635851 | 0.78 | HTR2A (0.42) | HTR6HTR2CHTR2AHTR2B | |
| SCHEMBL21268669 | 0.77 | NOTUM (0.42) | NOTUMPTGS2PTGS1PGR | |
| SCHEMBL8638141 | 0.74 | SIGMAR1 (0.52) | ASIC3PNMTHTR6HTR2CHTR2A | |
| SCHEMBL8350829 | 0.73 | AHR (0.48) | NOTUMASIC3PNMTHTR2CHTR2A | |
| SCHEMBL8640758 | 0.73 | HTR7 (0.41) | NOTUMASIC3PNMT | |
| SCHEMBL14895682 | 0.73 | PTGS2 (0.47) | NOTUMPTGS2PTGS1PGR | |
| SCHEMBL8639724 | 0.72 | HTR2C (0.56) | CYP2D6NOTUMASIC3PNMTHTR6 | |
| SCHEMBL387088 | 0.72 | TLR9 (0.49) | MLNRCYP2D6ASIC3PNMTKCNH2 | |
| SCHEMBL8347291 | 0.70 | PDE4A (0.46) | — | |
| SCHEMBL3383939 | 0.70 | HTR2C (0.62) | HTR6HTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |