Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8638173 | 0.87 | MMP9 (0.42) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL8644830 | 0.87 | MMP9 (0.42) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL8640416 | 0.83 | MME (0.53) | MEN1KMT2AHPGDHTT | |
| SCHEMBL8640345 | 0.83 | MME (0.53) | MEN1KMT2AHPGDHTT | |
| SCHEMBL8638471 | 0.78 | MMP2 (0.49) | ALDH1A1MEN1KMT2AHPGDMMP2 | |
| SCHEMBL8637603 | 0.77 | MMP9 (0.50) | ALDH1A1LMNAMMP2MMP9MMP8 | |
| SCHEMBL8639127 | 0.75 | BIRC2 (0.41) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL8638392 | 0.72 | LMNA (0.45) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL8641283 | 0.70 | MME (0.66) | HPGDADAMTS4MMP2MMP9 | |
| SCHEMBL8639879 | 0.70 | ACE (0.42) | LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766694-B1 | PEPTIDE DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 1998-08-05 | — | — | EP | claimed |
| EP-0766694-B1 | PEPTIDE DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 1998-08-05 | — | — | EP | disclosed |