Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639342 | 0.89 | ELANE (0.43) | ELANES1PR1S1PR3PPARALMNA | |
| SCHEMBL8640101 | 0.87 | PPARA (0.47) | ALDH1A1MMP1MMP2MMP13L3MBTL1 | |
| SCHEMBL8641923 | 0.82 | ELANE (0.42) | ELANES1PR1S1PR3PPARALMNA | |
| SCHEMBL8639942 | 0.81 | S1PR1 (0.43) | ELANES1PR1S1PR3PPARAS1PR4 | |
| SCHEMBL644718 | 0.77 | RIPK1 (0.44) | ALDH1A1ELANEL3MBTL1NPSR1ATM | |
| SCHEMBL8640088 | 0.77 | ELANE (0.45) | ELANES1PR1S1PR3PPARALMNA | |
| SCHEMBL1960388 | 0.76 | ELANE (0.49) | ALDH1A1ELANEL3MBTL1ATMLMNA | |
| SCHEMBL27859704 | 0.75 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1LMNACYP3A4TSHR | |
| SCHEMBL27859835 | 0.75 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1LMNACYP3A4TSHR | |
| SCHEMBL13727895 | 0.74 | L3MBTL1 (0.38) | ALDH1A1ELANEMMP1MMP2MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719306-A | ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |