SCHEMBL33707

SCHEMBL33707

OCCOCCc1c[c]ccc1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.36
TSHR P16473 1/20 0.36
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
TDP1 Q9NUW8 1/20 0.33
ALDH1A1 P00352 2/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.33
CASP1 P29466 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SLCO1B3 Q9NPD5 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
RECQL P46063 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19875946 0.90 MEN1 (0.37) MAPK1TSHRMEN1KMT2AALDH1A1
SCHEMBL27624397 0.81 TSHR (0.33) TSHR
SCHEMBL1167334 0.81
SCHEMBL18705909 0.80 RAB9A (0.36) MEN1KMT2ATDP1SMN1; SMN2CA1
SCHEMBL8640855 0.79 ALDH1A1 (0.43) MAPK1TSHRMEN1KMT2ATDP1
SCHEMBL8752385 0.79 TSHR (0.48) TSHRTDP1ALDH1A1SMN1; SMN2CA1
SCHEMBL1419465 0.77 LTA4H (0.41) MAPK1TDP1SMN1; SMN2CA2
SCHEMBL1180141 0.77 TDP1 (0.58) MAPK1TSHRMEN1KMT2ATDP1
Di(Hydroxyethyl)Ether SCHEMBL16085977 0.77 TDP1 (0.58) MAPK1TSHRMEN1KMT2ATDP1
SCHEMBL1167599 0.76 ENPP2 (0.35) TSHRLMNACA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 557 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3436428-B1 BISPHENOL M DIPHTHALONITRILE ETHER RESIN, BISPHENOL P DIPHTHALONITRILE ETHER RESIN, METHODS OF MAKING SAME, RESIN BLENDS, AND TWO COMPONENT SYSTEMS 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-07-10 EP disclosed
CN-118265569-A Method for purification of biological material 舒万诺知识产权公司 2024-06-28 CN disclosed
US-20240199920-A1 ARTICLES CONTAINING ADHESIVE COMPOSITIONS EXHIBITING ON-DEMAND DEBONDING BEHAVIOR 3M INNOVATIVE PROPERTIES COMPANY 2024-06-20 US disclosed
EP-4136070-B1 MONOMERS, POLYMERS, AND ARTICLES FOR BIOMATERIAL CAPTURE SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-05-29 EP disclosed
CN-115443266-B Monomers, polymers and articles for biomaterial capture 舒万诺知识产权公司 2024-05-17 CN disclosed
EP-4347246-A1 ARTICLES CONTAINING ADHESIVE COMPOSITIONS EXHIBITING ON-DEMAND DEBONDING BEHAVIOR 3M Innovative Properties Company (US) 2024-04-10 EP disclosed
EP-4107217-B1 POLYMERIZABLE COMPOSITIONS INCLUDING A PHTHALONITRILE RESIN AND A POLYOXOMETALATE, ARTICLES, AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-03-27 EP disclosed
US-11932750-B2 Resin blends including phthalonitrile resin and thiadiazole substituted phthalonitrile compound, articles, compounds, and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-03-19 US disclosed
CN-117412856-A Articles containing adhesive compositions exhibiting on-demand debonding behavior 3M创新有限公司 2024-01-16 CN disclosed
EP-3864002-B1 ADDITION-FRAGMENTATION AGENT WITH PENDENT AMINE GROUPS 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-12-27 EP disclosed
US-20100307680-A1 BENZOXAZINE-THIOL ADDUCTS 3M INNOVATIVE PROPERTIES COMPANY 2010-12-09 US disclosed
US-20100311861-A1 THIOL-YNE SHAPE MEMORY POLYMER 3M INNOVATIVE PROPERTIES COMPANY 2010-12-09 US disclosed
US-20100312004-A1 BENZOXAZINE-THIOL ADDUCTS 3M INNOVATIVE PROPERTIES COMPANY 2010-12-09 US disclosed
WO-2010141274-A1 THIOL-YNE SHAPE MEMORY POLYMER 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-12-09 WO disclosed
US-7442760-B2 Electroactive polymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-10-28 US disclosed
US-7094902-B2 Electroactive polymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-08-22 US disclosed
US-20060155106-A1 ELECTROACTIVE POLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2006-07-13 US disclosed
EP-1573789-A2 ELECTROACTIVE POLYMERS 3M Innovative Properties Company (US) 2005-09-14 EP disclosed
WO-2004102615-A2 ELECTROACTIVE POLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-11-25 WO disclosed
US-20040062930-A1 Electroactive polymers 3M INNOVATIVE PROPERTIES COMPANY 2004-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100312004-A1 BENZOXAZINE-THIOL ADDUCTS AOX1, GJA1, PRDX4 MAPK1 4754/4885TSHR 4761/4885MEN1 4858/4885
US-11932750-B2 Resin blends including phthalonitrile resin and thiadiazole substituted phthalonitrile compound, articles, compounds, and methods THUMPD1, RBBP5, RB1 MAPK1 3793/4885TSHR 3738/4885MEN1 2787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.