Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.49 |
| ▸ | RARG | P13631 | 7/20 | 0.49 |
| ▸ | RXRA | P19793 | 2/20 | 0.49 |
| ▸ | RARA | P10276 | 7/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6294271 | 0.78 | RXRA (0.49) | RARBRARGRXRARARA | |
| SCHEMBL6292438 | 0.73 | RXRA (0.40) | RARBRARGRXRARARA | |
| SCHEMBL7902107 | 0.72 | RARG (0.63) | RARBRARGRXRARARA | |
| SCHEMBL6292968 | 0.71 | RARB (0.62) | RARBRARGRXRARARA | |
| SCHEMBL10756175 | 0.70 | HTR7 (0.35) | IDO1 | |
| SCHEMBL7158656 | 0.70 | RXRA (0.48) | RARBRARGRXRARARA | |
| SCHEMBL6292476 | 0.69 | OPRM1 (0.36) | — | |
| SCHEMBL7265393 | 0.69 | RARG (0.63) | RARBRARGRXRARARA | |
| SCHEMBL12620654 | 0.69 | RARB (0.38) | RARBRARGRXRARARA | |
| SCHEMBL9551739 | 0.65 | RARB (0.69) | RARBRARGRXRARARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723666-A | USEFUL AS REGULATORS OF CELL PROLIFERATION AND DIFFERENTIATION | ALLERGAN (US) | 1998-03-03 | — | — | US | disclosed |