Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.46 |
| ▸ | HRH1 | P35367 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639539 | 0.82 | SLC22A1 (0.36) | HTR2AHRH1TDP1SLC6A2SLC6A4 | |
| SCHEMBL9231169 | 0.82 | LMNA (0.41) | AOC3LMNA | |
| SCHEMBL8641673 | 0.81 | HIF1A (0.35) | HTR2AHRH1TDP1SLC6A2SLC6A4 | |
| SCHEMBL8639009 | 0.80 | TAAR1 (0.42) | HTR2AHRH1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8147998 | 0.79 | ATM (0.34) | SLC6A4HTR2CKDM4E | |
| SCHEMBL8146390 | 0.78 | SCN1A (0.36) | SLC6A2SLC6A4SLC6A3LMNACHRM2 | |
| SCHEMBL8639222 | 0.76 | ADRA2A (0.38) | SLC6A2SLC6A4SLC6A3ADRA2AADRA2B | |
| SCHEMBL8645772 | 0.73 | TRPA1 (0.36) | LMNA | |
| SCHEMBL8642476 | 0.73 | ALDH1A1 (0.34) | SLC6A2SLC6A4SLC6A3LMNAOPRM1 | |
| SCHEMBL9493145 | 0.72 | HTR2A (0.59) | HTR2AHRH1TDP1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804569-A | ANTIINFLAMMATORY, ANTIARRHYMIC AND LOCAL ANESTHETIC AGENT | CLARION PHARMACEUTICALS INC. (US) | 1998-09-08 | — | — | US | disclosed |