Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PRF1 | P14222 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27802067 | 0.82 | ALDH1A1 (0.56) | PARGMAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL8652124 | 0.80 | PARG (0.47) | PARGMAPTLMNAMEN1HPGD | |
| SCHEMBL8615189 | 0.79 | PTGS2 (0.71) | PTGS2 | |
| SCHEMBL28820849 | 0.77 | PARG (0.55) | PARGMAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL8648041 | 0.76 | CA2 (0.61) | PTGS2CA12CA2CA9L3MBTL1 | |
| SCHEMBL8652111 | 0.76 | MAPT (0.50) | PARGMAPTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL349527 | 0.75 | MAPT (0.66) | PARGMAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL8645625 | 0.74 | PTGS2 (0.63) | PTGS2 | |
| SCHEMBL1968159 | 0.74 | ALOX5AP (0.59) | PARGALOX5APFEN1 | |
| SCHEMBL8650160 | 0.73 | PTGS2 (0.69) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843999-A | 2-phenylazulene derivatives and a manufacturing method of these compounds | KOTOBUKI SEIYAKU CO., LTD. (JP) | 1998-12-01 | — | — | US | disclosed |