Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PARG | Q86W56 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648049 | 0.88 | MAPT (0.46) | MAPTNPSR1PARGALDH1A1L3MBTL1 | |
| SCHEMBL8652124 | 0.84 | PARG (0.47) | MAPTNPSR1PARGALDH1A1L3MBTL1 | |
| SCHEMBL8646855 | 0.83 | PTGS2 (0.59) | ALDH1A1LMNAPTGS2SMN1; SMN2HTT | |
| SCHEMBL27802067 | 0.77 | ALDH1A1 (0.56) | MAPTPARGALDH1A1L3MBTL1LMNA | |
| SCHEMBL8647809 | 0.76 | PARG (0.54) | MAPTPARGALDH1A1L3MBTL1LMNA | |
| SCHEMBL8650648 | 0.74 | L3MBTL1 (0.52) | MAPTALDH1A1L3MBTL1LMNAPTGS2 | |
| SCHEMBL6163597 | 0.70 | GPR119 (0.53) | ALDH1A1PTGS2 | |
| SCHEMBL11227892 | 0.70 | LMNA (0.64) | MAPTALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL19397824 | 0.70 | FGFR1 (0.56) | MAPTNPSR1ALDH1A1LMNAMEN1 | |
| SCHEMBL349527 | 0.70 | MAPT (0.66) | MAPTNPSR1PARGALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843999-A | 2-phenylazulene derivatives and a manufacturing method of these compounds | KOTOBUKI SEIYAKU CO., LTD. (JP) | 1998-12-01 | — | — | US | disclosed |