Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.49 |
| ▸ | DRD4 | P21917 | 4/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648451 | 0.99 | HTR1A (0.55) | HTR1AMEN1KMT2AADRA1ADRD4 | |
| SCHEMBL8643772 | 0.91 | HTR1A (0.51) | HTR1AMEN1KMT2AADRA1ADRD4 | |
| SCHEMBL8644907 | 0.90 | HTR1A (0.53) | HTR1AMEN1KMT2AADRA1ADRD4 | |
| SCHEMBL8647825 | 0.78 | HTR1A (0.54) | HTR1AMEN1KMT2AADRA1ADRD4 | |
| SCHEMBL10753828 | 0.77 | IGF1R (0.63) | HTR1AMEN1KMT2AADRA1ADRD4 | |
| SCHEMBL6547111 | 0.77 | MAPT (0.53) | HTR1AMEN1KMT2AADRA1ADRD4 | |
| SCHEMBL6064337 | 0.77 | HTR1A (0.62) | HTR1AMEN1KMT2AADRA1ADRD4 | |
| SCHEMBL8651533 | 0.74 | HTR1A (0.57) | HTR1AMEN1KMT2AADRA1ADRD4 | |
| SCHEMBL10756919 | 0.74 | DRD2 (0.52) | HTR1AMEN1KMT2AADRA1ADRD4 | |
| SCHEMBL8644809 | 0.74 | HTR1A (0.52) | HTR1AMEN1KMT2AADRA1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690845-B1 | PIPERAZINE DERIVATIVES AS 5-HT1A LIGANDS | WYETH JOHN & BROTHER LTD (GB) | 1998-09-09 | — | — | EP | claimed |