Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557122 | 0.86 | GAA (0.42) | GAAALDH1A1HPGDLMNACYP1A2 | |
| SCHEMBL4433341 | 0.82 | GAA (0.40) | GAAALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL812401 | 0.81 | PGR (0.40) | GAAALDH1A1CASP1HTTSMN1; SMN2 | |
| SCHEMBL6207998 | 0.72 | ALDH1A1 (0.49) | GAAALDH1A1KDM4EHPGDCASP1 | |
| SCHEMBL812403 | 0.72 | SMN1; SMN2 (0.43) | GAAALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL812402 | 0.72 | PGR (0.49) | ALDH1A1HPGDMAPTTSHRPGR | |
| SCHEMBL6207995 | 0.72 | PGR (0.40) | GAAALDH1A1KDM4EHPGDCASP1 | |
| SCHEMBL7098246 | 0.70 | ALDH1A1 (0.38) | GAAALDH1A1HPGDLMNAALOX12 | |
| SCHEMBL10752583 | 0.70 | GAA (1.00) | GAAALDH1A1KDM4EHPGDHTT | |
| SCHEMBL9595577 | 0.69 | ALDH1A1 (0.40) | GAAALDH1A1KDM4EHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0521334-B1 | Substituted 1-H-3-aryl-pyrrolidin-2,4-dione derivatives, their preparation and their use as insecticides, acaricides and herbicides | BAYER AG (DE) | 1998-09-09 | — | — | EP | disclosed |
| US-5616536-A | INSECTICIDES, MITICIDES, HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |
| EP-0456063-B1 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |
| US-5589469-A | INSECTICIDES, MITICIDES OR HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-31 | — | — | US | disclosed |
| EP-0521334-A1 | Substituted 1-H-3-aryl-pyrrolidin-2,4-dione derivatives | BAYER AG (DE) | 1993-01-07 | — | — | EP | disclosed |