Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 4/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812401 | 0.89 | PGR (0.40) | PGRSMN1; SMN2ESR2CREBBPBRPF1 | |
| SCHEMBL7098243 | 0.80 | ESR2 (0.35) | SMN1; SMN2ESR2CREBBPBRD4ALDH1A1 | |
| SCHEMBL812402 | 0.75 | PGR (0.49) | PGRMAPTALDH1A1HPGD | |
| SCHEMBL7098248 | 0.72 | ELANE (0.36) | SMN1; SMN2TNKS2MAPTALDH1A1KDM4E | |
| SCHEMBL8650400 | 0.72 | GAA (0.54) | PGRSMN1; SMN2TNKS2MAPTTHRB | |
| SCHEMBL6207998 | 0.70 | ALDH1A1 (0.49) | SMN1; SMN2TNKS2MAPTTHRBCASP1 | |
| SCHEMBL2962371 | 0.69 | MKNK2 (0.32) | — | |
| SCHEMBL3826053 | 0.67 | PGR (0.33) | PGR | |
| SCHEMBL6832170 | 0.67 | ELANE (0.36) | GAA | |
| SCHEMBL4433341 | 0.65 | GAA (0.40) | ALDH1A1KDM4EMEN1USP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066258-B1 | ARYL PHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2005-12-14 | — | — | EP | disclosed |
| US-6806264-B2 | PESTICIDES AND HERBICIDES; WOOD PROTECTANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-10-19 | — | — | US | disclosed |
| US-20040127365-A1 | Arylphenyl-substituted cyclic ketoenols | LIEB FOLKER (DE) | 2004-07-01 | — | — | US | disclosed |
| US-6693092-B2 | HERBICIDES; PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-02-17 | — | — | US | disclosed |
| US-20030073851-A1 | Arylphenyl-substituted cyclic ketoenols | LIEB FOLKER (DE) | 2003-04-17 | — | — | US | disclosed |
| US-6458965-B1 | HERBICIDES, ANTIGROWTH AGENTS AND SURFACTANTS FOR WOOD PRESERVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-01 | — | — | US | disclosed |
| EP-1066258-A1 | ARYL PHENYL SUBSTITUTED CYCLIC KETOENOLS | Bayer Aktiengesellschaft (DE) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999048869-A1 | ARYL PHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073851-A1 | Arylphenyl-substituted cyclic ketoenols | KCNE1, CYP2E1, CYP21A2 | PGR 906/4885SMN1; SMN2 4667/4885ESR2 1416/4885 |
| US-20040127365-A1 | Arylphenyl-substituted cyclic ketoenols | KCNE1, CYP2E1, CYP21A2 | PGR 906/4885SMN1; SMN2 4667/4885ESR2 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.