Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207995 | 0.89 | PGR (0.40) | PGRESR2ALDH1A1HTTGAA | |
| SCHEMBL8650400 | 0.81 | GAA (0.54) | PGRALDH1A1HTTGAASMN1; SMN2 | |
| SCHEMBL7098243 | 0.80 | ESR2 (0.35) | ESR2ALDH1A1HTTGAASMN1; SMN2 | |
| SCHEMBL812402 | 0.78 | PGR (0.49) | PGRALDH1A1MAPT | |
| SCHEMBL6832170 | 0.75 | ELANE (0.36) | GAA | |
| SCHEMBL6207998 | 0.70 | ALDH1A1 (0.49) | ALDH1A1GAASMN1; SMN2TNKS2MAPT | |
| SCHEMBL7098248 | 0.69 | ELANE (0.36) | ALDH1A1SMN1; SMN2PTGESTNKS2MAPT | |
| SCHEMBL4433341 | 0.68 | GAA (0.40) | ALDH1A1GAA | |
| SCHEMBL811954 | 0.65 | ESR2 (0.43) | PGRESR2HTTSMN1; SMN2MAPT | |
| SCHEMBL812654 | 0.65 | PGR (0.50) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058210-B2 | Arylphenyl-substituted cyclic keto-enols | BAYER CROPSCIENCE AG (DE) | 2011-11-15 | — | — | US | disclosed |
| US-7718706-B2 | Arylphenyl-substituted cyclic keto-enols | BAYER AKTIENGESELLSCHAFT (DE) | 2010-05-18 | — | — | US | disclosed |
| US-20100087320-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | LIEB FOLKER | 2010-04-08 | — | — | US | disclosed |
| US-20080081807-A1 | Arylphenyl-substituted cyclic keto-enols | LIEB FOLKER | 2008-04-03 | — | — | US | disclosed |
| US-7288676-B2 | Arylphenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-10-30 | — | — | US | disclosed |
| US-7105471-B2 | Arylphenyl-substituted cyclic ketoenols | BAYER AKTIENGESELLSCHAFT (DE) | 2006-09-12 | — | — | US | disclosed |
| US-20060122061-A1 | Arylphenyl-substituted cyclic ketoenols | LIEB FOLKER | 2006-06-08 | — | — | US | disclosed |
| EP-1056717-B1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | BAYER CROPSCIENCE AG (DE) | 2005-07-20 | — | — | EP | disclosed |
| US-6716832-B2 | PESTICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-04-06 | — | — | US | disclosed |
| US-20020188136-A1 | Arylphenyl-substituted cyclic ketoenols | LIEB FOLKER (DE) | 2002-12-12 | — | — | US | disclosed |
| US-6417370-B1 | HERBICIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-09 | — | — | US | disclosed |
| EP-1056717-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | Bayer Aktiengesellschaft (DE) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999043649-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122061-A1 | Arylphenyl-substituted cyclic ketoenols | KCNE1, KCNQ3, KCNQ2 | PGR 1039/4885ESR2 1670/4885ALDH1A1 2523/4885 |
| US-20080081807-A1 | Arylphenyl-substituted cyclic keto-enols | KCNE1, DDT, KCNQ3 | PGR 1538/4885ESR2 1810/4885ALDH1A1 2569/4885 |
| US-20100087320-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | KCNE1, DDT, KCNQ3 | PGR 1538/4885ESR2 1810/4885ALDH1A1 2569/4885 |
| US-20020188136-A1 | Arylphenyl-substituted cyclic ketoenols | KCNE1, CYP21A2, KCNQ3 | PGR 994/4885ESR2 1398/4885ALDH1A1 1648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.