SCHEMBL213561

SCHEMBL213561

Cc1nc(C(=O)O)c(C(=O)O)[nH]1

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 8/20 0.48
CYP1A2 P05177 1/20 0.48
MAPK1 P28482 1/20 0.48
CASP1 P29466 1/20 0.48
CYP2C19 P33261 1/20 0.48
HSP90AA1 P07900 1/20 0.38
ESR2 Q92731 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HCAR2 Q8TDS4 3/20 0.36
ALDH1A1 P00352 1/20 0.36
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8077442 0.85 PIN1 (0.37) PIN1CYP1A2MAPK1CASP1CYP2C19
SCHEMBL8077446 0.85 PARP1 (0.38) PIN1CYP1A2MAPK1CASP1CYP2C19
SCHEMBL8919174 0.79 PIN1 (0.53) PIN1CYP1A2MAPK1CASP1CYP2C19
SCHEMBL3023228 0.79 HSP90AA1 (0.39) PIN1CYP1A2MAPK1CASP1CYP2C19
SCHEMBL27571567 0.77 PIN1 (0.39) PIN1HSP90AA1ESR2TDP1HCAR2
SCHEMBL3032708 0.76 GPR35 (0.37) PIN1CYP1A2MAPK1CASP1CYP2C19
SCHEMBL3023200 0.76 ALDH1A1 (0.38) PIN1CYP1A2MAPK1CASP1CYP2C19
SCHEMBL5433660 0.76 PIN1 (0.38) PIN1CYP1A2HSP90AA1ESR2TDP1
SCHEMBL28169947 0.74 PIN1 (0.50) PIN1CYP1A2MAPK1CASP1CYP2C19
SCHEMBL11475671 0.74 PIN1 (0.50) PIN1CYP1A2MAPK1CASP1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 440 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042084-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP GENERAL ELECTRIC TECHNOLOGY GMBH (CH) 2026-02-12 US claimed
EP-4680369-A1 SYSTEMS FOR CARBON DIOXIDE CAPTURE USING FUNCTIONALIZED SORBENTS AND WATER MANAGEMENT GE Vernova Technology GmbH (CH) 2026-01-21 EP claimed
US-20250354659-A1 SYSTEM AND METHOD FOR STORING LIQUIDS HAVING LOW LATENT HEAT OF VAPORIZATION NUOVO PIGNONE TECNOLOGIE – S R L (IT) 2025-11-20 US claimed
EP-4572884-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP General Electric Technology GmbH (CH) 2025-06-25 EP claimed
EP-4556112-A2 SORBENT COMPOSITIONS, SYSTEMS, AND METHODS General Electric Technology GmbH (CH) 2025-05-21 EP claimed
CN-119869460-A Sorbent compositions, systems, and methods 通用电气技术有限公司 2025-04-25 CN claimed
US-12263464-B2 Method for in-situ synthesis of metal organic frameworks (MOFs), covalent organic frameworks (COFs) and zeolite imidazolate frameworks (ZIFs), and applications thereof DESICCANT ROTORS INTERNATIONAL PRIVATE LIMITED (IN) 2025-04-01 US claimed
CN-119656892-A Hydrolyzed polyacrylonitrile-based zeolite imidazole framework membrane for ammonia separation and preparation method thereof 福州大学 2025-03-21 CN claimed
CN-119056492-A Filter membrane for removing DNA pollution in water and preparation method and application thereof 中国科学院长春应用化学研究所 2024-12-03 CN claimed
CN-118950092-A MOF material with nuclease-like activity and preparation method and application thereof 中国科学院长春应用化学研究所 2024-11-15 CN claimed
CN-109055447-A A kind of supercritical CO2The method that technique immobilized enzyme catalysis prepares 1,3 diglycerides 江苏大学 2018-12-21 CN claimed
CN-103012501-B Zn-Tb coordination polymer luminescent material based on like-amino acid ligand and preparation method thereof UNIV LUOYANG NORMAL 2015-03-11 CN claimed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20140311507-A1 Porous Catalytic Matrices for Elimination of Toxicants Found in Tobacco Combustion Products MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-10-23 US claimed
EP-2739169-A2 POROUS CATALYTIC MATRICES FOR ELIMINATION OF TOXICANTS FOUND IN TOBACCO COMBUSTION PRODUCTS Massachusetts Institute Of Technology (US) 2014-06-11 EP claimed
CN-103012501-A Zn-Tb coordination polymer luminescent material based on like-amino acid ligand and preparation method thereof UNIV LUOYANG NORMAL 2013-04-03 CN claimed
WO-2013019865-A2 POROUS CATALYTIC MATRICES FOR ELIMINATION OF TOXICANTS FOUND IN TOBACCO COMBUSTION PRODUCTS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-02-07 WO claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
US-4662905-A REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) 1987-05-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042084-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP SRMS, TYRO3, SELE PIN1 4360/4885CYP1A2 2002/4885MAPK1 3579/4885
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 PIN1 44/4885CYP1A2 3261/4885MAPK1 2309/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA PIN1 1587/4885CYP1A2 1104/4885MAPK1 2694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.