Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795724 | 0.86 | SMN1; SMN2 (0.52) | — | |
| SCHEMBL4629761 | 0.86 | TDP1 (0.38) | TDP1KDM4ENPSR1ALDH1A1NPC1 | |
| SCHEMBL11598307 | 0.86 | ALDH1A1 (0.41) | TDP1KDM4EALDH1A1HTTKMT2A | |
| SCHEMBL9795734 | 0.84 | OGG1 (0.38) | KDM4EALDH1A1KMT2ATSHRL3MBTL1 | |
| SCHEMBL8652157 | 0.83 | ALDH1A1 (0.50) | TDP1KDM4EALDH1A1NPC1HTT | |
| SCHEMBL9795706 | 0.82 | CYP3A4 (0.41) | NPSR1ALDH1A1NPC1POLBHTT | |
| SCHEMBL9795602 | 0.82 | ALDH1A1 (0.41) | TDP1KDM4EALDH1A1POLBRAB9A | |
| SCHEMBL11649665 | 0.81 | MTNR1A (0.46) | TDP1KDM4EALDH1A1HTTKMT2A | |
| SCHEMBL9795628 | 0.80 | SIGMAR1 (0.45) | TDP1KDM4ETSHR | |
| SCHEMBL28146500 | 0.80 | KDM4E (0.56) | TDP1KDM4ENPSR1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4091227-A | ANTIBACTERIAL AGENTS | SMITHKLINE CORPORATION (US) | 1978-05-23 | — | — | US | disclosed |
| US-4067978-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4067977-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4067976-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4007173-A | BACTERICIDE | SMITHKLINE CORPORATION (US) | 1977-02-08 | — | — | US | disclosed |