Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.61 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.61 |
| ▸ | MIF | P14174 | 1/20 | 0.56 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.56 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 3/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2781980 | 1.00 | ALDH1A1 (0.61) | ALDH1A1KDM4EPKMPTGER3PTGDR | |
| SCHEMBL865293 | 1.00 | ALDH1A1 (0.61) | ALDH1A1KDM4EPKMPTGER3PTGDR | |
| SCHEMBL865803 | 0.87 | HDAC8 (0.57) | ALDH1A1KDM4EPKMPTGER3PTGDR | |
| SCHEMBL865802 | 0.87 | HDAC8 (0.57) | ALDH1A1KDM4EPKMPTGER3PTGDR | |
| SCHEMBL1723809 | 0.87 | HDAC8 (0.57) | ALDH1A1KDM4EPKMPTGER3PTGDR | |
| SCHEMBL16516226 | 0.86 | ALDH1A1 (0.64) | ALDH1A1KDM4EPKMPTGER3PTGDR | |
| SCHEMBL16516225 | 0.86 | ALDH1A1 (0.64) | ALDH1A1KDM4EPKMPTGER3PTGDR | |
| SCHEMBL7909151 | 0.85 | PTGER3 (0.68) | ALDH1A1KDM4EPKMPTGER3PTGDR | |
| SCHEMBL7191225 | 0.85 | PTGER3 (0.68) | ALDH1A1KDM4EPKMPTGER3PTGDR | |
| SCHEMBL16848326 | 0.84 | ALDH1A1 (0.61) | ALDH1A1KDM4EPKMPTGER3PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077793-A1 | Compounds for the Treatment of Metabolic Disorders | PROSIDION LIMITED (GB) | 2012-03-29 | — | — | US | disclosed |
| US-20100286112-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-11-11 | — | — | US | disclosed |
| WO-2010103333-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |
| EP-2200609-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | Prosidion Limited (GB) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009034388-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286112-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | GPR119, DPP4, DPP9 | ALDH1A1 914/4885KDM4E 2245/4885PKM 1485/4885 |
| US-20120077793-A1 | Compounds for the Treatment of Metabolic Disorders | GPR119, GPR132, FFAR2 | ALDH1A1 1300/4885KDM4E 3483/4885PKM 1490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.