Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1E | P28566 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | AQP3 | Q92482 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GCGR | P47871 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8886708 | 0.88 | ADRA1D (0.34) | HTR1ES1PR3ATMAQP3ALPL | |
| SCHEMBL6474821 | 0.87 | NPSR1 (0.40) | ALDH1A1NPSR1 | |
| SCHEMBL8657002 | 0.86 | HTR1E (0.36) | HTR1ES1PR3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8654470 | 0.84 | HTR1E (0.38) | HTR1ES1PR3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8650594 | 0.83 | ALDH1A1 (0.39) | HTR1ES1PR3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8654101 | 0.83 | HTR1E (0.34) | HTR1ES1PR3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8652494 | 0.83 | KEAP1 (0.35) | HTR1ES1PR3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8654879 | 0.82 | PYGL (0.39) | HTR1ES1PR3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8657354 | 0.82 | PYGL (0.39) | HTR1ES1PR3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8663533 | 0.82 | PYGL (0.39) | HTR1ES1PR3ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847211-A | Substituted 1H-3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| US-5622917-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |