Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537370 | 0.93 | MAT2A (0.43) | MAT2ACREBBPKLKB1ALKKCNH2 | |
| SCHEMBL8538579 | 0.91 | MAT2A (0.61) | MAT2ACREBBPCYP19A1KLKB1KCNH2 | |
| SCHEMBL8533234 | 0.91 | MAT2A (0.49) | MAT2ACREBBPCYP19A1KLKB1KCNH2 | |
| SCHEMBL8513871 | 0.89 | MAT2A (0.46) | MAT2ACREBBPKLKB1KCNH2TYMS | |
| SCHEMBL8536502 | 0.85 | MAT2A (0.43) | MAT2ACREBBPKLKB1KCNH2TYMS | |
| SCHEMBL8533461 | 0.83 | MAT2A (0.56) | MAT2ACYP19A1MAPK1 | |
| SCHEMBL19002091 | 0.80 | MAT2A (0.44) | MAT2AKCNH2CHRM5ADORA2BADORA2A | |
| SCHEMBL8536444 | 0.79 | MAT2A (0.64) | MAT2ACYP19A1KCNH2MAPK1 | |
| SCHEMBL8535741 | 0.78 | ABL1 (0.41) | CREBBPKLKB1KCNH2CHRM5ADORA2B | |
| SCHEMBL8531391 | 0.78 | CREBBP (0.40) | CREBBPKLKB1KCNH2CHRM5ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | claimed |
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |