Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8513871 | 0.89 | MAT2A (0.46) | ABL1BCRNPBWR1CREBBPKIF11 | |
| SCHEMBL8531391 | 0.87 | CREBBP (0.40) | ABL1BCRCREBBPKIF11CHRM5 | |
| SCHEMBL19002099 | 0.87 | KDM5B (0.42) | ABL1BCRCREBBPKIF11CHRM5 | |
| SCHEMBL8537027 | 0.84 | ALDH1A1 (0.41) | CREBBPMAPK8MAPK10KLKB1ADORA3 | |
| SCHEMBL8534905 | 0.83 | CTSV (0.47) | ABL1BCRCREBBPKIF11CHRM5 | |
| SCHEMBL8537609 | 0.82 | KIF11 (0.44) | KIF11CHRM5HCRTR1HCRTR2 | |
| SCHEMBL8533234 | 0.80 | MAT2A (0.49) | ABL1BCRCREBBPCHRM5KLKB1 | |
| SCHEMBL8536502 | 0.80 | MAT2A (0.43) | ABL1BCRCREBBPCHRM5KLKB1 | |
| SCHEMBL19002091 | 0.80 | MAT2A (0.44) | ABL1KIF11CHRM5KCNH2ADORA2A | |
| SCHEMBL8537370 | 0.78 | MAT2A (0.43) | ABL1BCRCREBBPCHRM5KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | claimed |
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |