Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATG7 | O95352 | 19/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10149295 | 1.00 | ATG7 (0.49) | ATG7 | |
| SCHEMBL866845 | 0.83 | ATG7 (0.51) | ATG7 | |
| Formycin SCHEMBL10149284 | 0.82 | HIF1A (0.55) | — | |
| Formycin SCHEMBL4196088 | 0.82 | HIF1A (0.55) | — | |
| SCHEMBL10149280 | 0.81 | IMPDH2 (0.40) | ATG7 | |
| SCHEMBL867383 | 0.77 | ATG7 (0.49) | ATG7 | |
| SCHEMBL867144 | 0.77 | ATG7 (0.49) | ATG7 | |
| SCHEMBL866882 | 0.77 | ATG7 (0.48) | ATG7 | |
| SCHEMBL866573 | 0.77 | ATG7 (0.48) | ATG7 | |
| SCHEMBL2294870 | 0.71 | CA1 (0.73) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077814-A1 | SULFONAMIDE, SULFAMATE, AND SULFAMOTHIOATE DERIVATIVES | WANG ZHONG (US) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077814-A1 | SULFONAMIDE, SULFAMATE, AND SULFAMOTHIOATE DERIVATIVES | NEDD8, NAE1, UBA3 | ATG7 798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.