Formycin

Formycin

SCHEMBL4196088

Nc1ncnc2c([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)[nH]nc12

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 2/20 0.55
▸ GAPDH P04406 2/20 0.47
▸ ADORA3 P0DMS8 2/20 0.47
▸ SLC28A2 O43868 2/20 0.47
▸ DPP4 P27487 1/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ SLC28A1 O00337 1/20 0.47
▸ MAP3K7 O43318 1/20 0.47
▸ MAPK1 P28482 1/20 0.47
▸ ADORA2A P29274 1/20 0.47
▸ ADORA2B P29275 1/20 0.47
▸ ADORA1 P30542 1/20 0.47
▸ STAT6 P42226 1/20 0.47
▸ PI4KA P42356 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ PI4K2B Q8TCG2 1/20 0.47
▸ DOT1L Q8TEK3 1/20 0.47
▸ SLC29A1 Q99808 1/20 0.47
▸ PI4K2A Q9BTU6 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formycin SCHEMBL10149284 1.00 HIF1A (0.55) HIF1AGAPDHADORA3SLC28A2DPP4
SCHEMBL5071995 0.85 HIF1A (0.44) HIF1ASTAT6SMN1; SMN2SLC29A1PNP
SCHEMBL10149295 0.82 ATG7 (0.49) —
SCHEMBL10149280 0.82 IMPDH2 (0.40) HIF1APNP
SCHEMBL865526 0.82 ATG7 (0.49) —
SCHEMBL29941387 0.81 YTHDC1 (0.45) HIF1AADORA3ADORA1SLC29A1HSPA8
Formycin SCHEMBL14074914 0.80 HIF1A (0.61) HIF1AGAPDHADORA3SLC28A2DPP4
Formycin SCHEMBL15262901 0.80 HIF1A (0.61) HIF1AGAPDHADORA3SLC28A2DPP4
Formycin SCHEMBL980049 0.80 HIF1A (0.61) HIF1AGAPDHADORA3SLC28A2DPP4
SCHEMBL29941437 0.79 PNP (0.41) HIF1APNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 — — US claimed
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2024-05-02 — — US claimed
US-11725227-B2 Devices and methods for examining drug effects on microorganisms ESSENLIX CORPORATION (US) 2023-08-15 — — US claimed
EP-4045504-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS Ai-biopharma (FR) 2022-08-24 — — EP claimed
CN-114901657-A Antiviral and liver-targeting drugs 人工智能生物制药公司 2022-08-12 — — CN claimed
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 — — US disclosed
US-20260138999-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS BRISTOL MYERS SQUIBB CO (US) 2026-05-21 — — US disclosed
US-12570676-B2 Multifunctionalized silicon nanoparticles, process for their preparation and uses thereof in electrochemiluminescence based detection methods ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2026-03-10 — — US disclosed
EP-4695391-A1 TREMS FOR USE IN CORRECTION OF MISSENSE MUTATIONS Flagship Pioneering Innovations VI, LLC (US) 2026-02-18 — — EP disclosed
US-12539332-B2 Anti-viral and hepatic-targeted drugs A-BIOPHARMA (FR) 2026-02-03 — — US disclosed
US-20260027191-A1 COMPOSITIONS AND METHODS FOR TREATING BACTERIAL DISEASE UNIV ARIZONA (US) 2026-01-29 — — US disclosed
US-12527739-B2 Aqueous pharmaceutical compositions comprising benzyl atropine and uses thereof ALCON INC. (CH) 2026-01-20 — — US disclosed
EP-2600868-B1 COMBINATION OF A PYRROLOQUINOLINE COMPOUND AND AN AMINOGLYCODISE ANTIMICROBIAL AGENT HELPERBY THERAPEUTICS LTD (GB) 2022-03-09 — — EP disclosed
US-11267827-B2 Multifunctionalized silicon nanoparticles, process for their preparation and uses thereof in electrochemiluminescence based detection methods ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2022-03-08 — — US disclosed
CN-114105916-A RyR2 stabilizer, preparation method thereof, corresponding pharmaceutical composition and application 深圳大学 2022-03-01 — — CN disclosed
CN-114007695-A As AM2Heterocyclic spiro-compounds as receptor inhibitors 谢菲尔德大学 2022-02-01 — — CN disclosed
WO-2009099676-A1 TYPE 5 ADENYLYL CYCLASE INHIBITORS FOR PROVIDING CARDIAC PROTECTION UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) 2009-08-13 — — WO disclosed
US-7368437-B1 Bicyclic heterocycles, processes for their preparation and their use as herbicides and pharmaceutical agents BAYER CROPSCIENCE AG (DE) 2008-05-06 — — US disclosed
EP-1165563-B1 BICYCLIC HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS HERBICIDES AND PHARMACEUTICAL AGENTS BAYER CROPSCIENCE GMBH (DE) 2005-03-02 — — EP disclosed
US-4028184-A CULTURING CORYNEBACTERIUM, ARTHROBACTER, MICROBACTERIUM KIKKOMAN SHOYU CO., LTD. (JA) 1977-06-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570676-B2 Multifunctionalized silicon nanoparticles, process for their preparation and uses thereof in electrochemiluminescence based detection methods SELP, SELPLG, SELE HIF1A 2360/4885GAPDH 1742/4885ADORA3 4536/4885
US-12539332-B2 Anti-viral and hepatic-targeted drugs HAVCR2, NR1H4, NR1H3 HIF1A 3257/4885GAPDH 3766/4885ADORA3 580/4885
US-12527739-B2 Aqueous pharmaceutical compositions comprising benzyl atropine and uses thereof MYOC, MYO1G, MYH10 HIF1A 2962/4885GAPDH 964/4885ADORA3 1753/4885
US-20260138999-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS RNGTT, CDA, DCTD HIF1A 4457/4885GAPDH 2247/4885ADORA3 100/4885
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS HAVCR2, NR1H4, NR1H3 HIF1A 3160/4885GAPDH 3580/4885ADORA3 558/4885
US-11267827-B2 Multifunctionalized silicon nanoparticles, process for their preparation and uses thereof in electrochemiluminescence based detection methods SELE, SIK1, SIK2 HIF1A 2904/4885GAPDH 1690/4885ADORA3 4775/4885
US-20260027191-A1 COMPOSITIONS AND METHODS FOR TREATING BACTERIAL DISEASE DNMT3L, DNMT3A, DNMT1 HIF1A 4581/4885GAPDH 328/4885ADORA3 997/4885
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS SLC10A1, HAVCR2, HDGF HIF1A 3038/4885GAPDH 536/4885ADORA3 3777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback