Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659155 | 0.93 | CYP1A2 (0.37) | HTR7CHRM2CHRM1KDM1A | |
| SCHEMBL8659558 | 0.91 | HTR7 (0.38) | HTR7CHRM2CHRM1KDM4EALDH1A1 | |
| SCHEMBL8659185 | 0.91 | GLA (0.36) | HTR7GLAALDH1A1TP53 | |
| SCHEMBL8658434 | 0.89 | HTR7 (0.32) | HTR7GLACHRM2CHRM1 | |
| SCHEMBL8658396 | 0.87 | HTR7 (0.41) | HTR7CHRM2CHRM1 | |
| SCHEMBL8655407 | 0.86 | HTR7 (0.40) | HTR7CHRM2CHRM1KDM4EALDH1A1 | |
| SCHEMBL8655832 | 0.85 | HTR7 (0.37) | HTR7CHRM2CHRM1 | |
| SCHEMBL8657958 | 0.84 | ITGB3 (0.32) | GLA | |
| SCHEMBL8657207 | 0.84 | GLA (0.39) | GLAALDH1A1KDM1A | |
| SCHEMBL8659172 | 0.84 | S1PR5 (0.34) | HTR7CHRM2CHRM1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |