Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 6/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 6/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 6/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 3/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655367 | 0.94 | TPSAB1 (0.33) | TPSAB1TPSD1TPSG1PKMRECQL | |
| SCHEMBL8654586 | 0.94 | TPSAB1 (0.33) | TPSAB1TPSD1TPSG1PKMRECQL | |
| SCHEMBL8656251 | 0.90 | SMN1; SMN2 (0.34) | TPSAB1TPSD1TPSG1SMN1; SMN2 | |
| SCHEMBL8658063 | 0.89 | ITGB3 (0.34) | TPSAB1TPSD1TPSG1PKMRECQL | |
| SCHEMBL8660886 | 0.89 | ITGB3 (0.32) | PKMRECQLSMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL8655698 | 0.88 | GAA (0.32) | PKMSMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL8656289 | 0.87 | OPRL1 (0.33) | ITGB3ITGA2B | |
| SCHEMBL8661310 | 0.86 | SMN1; SMN2 (0.39) | TPSAB1TPSD1TPSG1SMN1; SMN2F2 | |
| SCHEMBL8655580 | 0.86 | SMN1; SMN2 (0.39) | TPSAB1TPSD1TPSG1SMN1; SMN2F2 | |
| SCHEMBL8661852 | 0.85 | SMN1; SMN2 (0.34) | TPSAB1TPSD1TPSG1SMN1; SMN2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |