Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.41 |
| ▸ | ACLY | P53396 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661075 | 0.89 | CYTH2 (0.48) | CYTH2FFAR4TSHRSMN1; SMN2KAT6A | |
| SCHEMBL8657894 | 0.89 | L3MBTL1 (0.44) | CYTH2ACLYHTR6KAT6AMEN1 | |
| SCHEMBL8661104 | 0.88 | CYTH2 (0.48) | CYTH2FFAR4TSHRMEN1KMT2A | |
| SCHEMBL8661475 | 0.88 | PTGS2 (0.46) | CYTH2FFAR4ACLYKAT6AMEN1 | |
| SCHEMBL8659865 | 0.86 | KAT6A (0.45) | CYTH2FFAR4ACLYHTR6KAT6A | |
| SCHEMBL8656754 | 0.86 | PGR (0.48) | STAT3CYTH2FFAR4SMN1; SMN2KAT6A | |
| SCHEMBL8656166 | 0.85 | GAA (0.44) | CYTH2FFAR4TSHRSMN1; SMN2KAT6A | |
| SCHEMBL8657865 | 0.85 | CYTH2 (0.49) | CYTH2FFAR4TSHRKAT6AMEN1 | |
| SCHEMBL8661766 | 0.85 | PTGS2 (0.48) | STAT3ACLYHTR6KMT2A | |
| SCHEMBL8661452 | 0.84 | SLC40A1 (0.45) | CYTH2FFAR4ACLYTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |