Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659185 | 0.86 | GLA (0.36) | GLACYP1A2ALDH1A1 | |
| SCHEMBL8656240 | 0.86 | PKM (0.35) | GLAPKMCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL8658344 | 0.85 | GLA (0.33) | GLACYP1A2MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8656805 | 0.84 | HTR7 (0.38) | GLAKDM1AALDH1A1 | |
| SCHEMBL8657958 | 0.83 | ITGB3 (0.32) | GLAMAPK1 | |
| SCHEMBL8657859 | 0.81 | ITGB3 (0.32) | GLAMAPK1 | |
| SCHEMBL8658466 | 0.81 | CYP1A2 (0.38) | PKMKDM1ACYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL8655169 | 0.81 | MAOB (0.35) | GLACYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL8659051 | 0.81 | ACHE (0.33) | GLAKDM1A | |
| SCHEMBL8659258 | 0.80 | ITGB3 (0.33) | GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |