Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDCBP | O00560 | 3/20 | 0.53 |
| ▸ | SDC2 | P34741 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 4/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558519 | 1.00 | SDCBP (0.53) | SDCBPSDC2TSHRHSD17B10P2RX7 | |
| SCHEMBL8558470 | 0.88 | FPR2 (0.44) | SDCBPSDC2TSHRP2RX7ALDH1A1 | |
| SCHEMBL8558467 | 0.88 | FPR2 (0.44) | SDCBPSDC2TSHRP2RX7ALDH1A1 | |
| SCHEMBL8557162 | 0.87 | ALDH1A1 (0.57) | P2RX7ALDH1A1NPSR1THRB | |
| SCHEMBL8657482 | 0.87 | ALDH1A1 (0.57) | P2RX7ALDH1A1NPSR1THRB | |
| SCHEMBL8554540 | 0.86 | SHMT1 (0.50) | TSHRHSD17B10P2RX7HTR2AHTR2C | |
| SCHEMBL8554539 | 0.86 | SHMT1 (0.50) | TSHRHSD17B10P2RX7HTR2AHTR2C | |
| SCHEMBL4426579 | 0.83 | SDCBP (0.50) | SDCBPSDC2TSHRHSD17B10ALDH1A1 | |
| SCHEMBL4426577 | 0.83 | SDCBP (0.50) | SDCBPSDC2TSHRHSD17B10ALDH1A1 | |
| SCHEMBL6996825 | 0.83 | MEN1 (0.47) | SDCBPSDC2ALDH1A1NPSR1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847211-A | Substituted 1H-3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| EP-0668267-B1 | Substituted 1H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1998-04-08 | — | — | EP | disclosed |
| US-5622917-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| EP-0668267-A1 | Substituted 1H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |