Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | RGS12 | O14924 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659391 | 0.93 | HTR7 (0.39) | HTR7SIGMAR1CHRM2CHRM1ALDH1A1 | |
| SCHEMBL8655832 | 0.91 | HTR7 (0.37) | HTR7SLC18A3CHRM2CHRM1GAA | |
| SCHEMBL8659153 | 0.90 | HTR7 (0.37) | HTR7CHRM2CHRM1GAAGRIN1 | |
| SCHEMBL8657758 | 0.90 | SIGMAR1 (0.35) | SIGMAR1 | |
| SCHEMBL8659308 | 0.89 | SIGMAR1 (0.35) | HTR7SIGMAR1SLC18A3CHRM2CHRM1 | |
| SCHEMBL8659427 | 0.89 | HTR7 (0.41) | HTR7SIGMAR1CHRM2CHRM1GRIN1 | |
| SCHEMBL8658434 | 0.85 | HTR7 (0.32) | HTR7CHRM2CHRM1GAA | |
| SCHEMBL8656730 | 0.84 | ITGB3 (0.33) | ITGB3ITGA2B | |
| SCHEMBL8659558 | 0.84 | HTR7 (0.38) | HTR7SIGMAR1CHRM2CHRM1ALDH1A1 | |
| SCHEMBL8659172 | 0.84 | S1PR5 (0.34) | HTR7CHRM2CHRM1GAAITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |