Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY2 | Q08462 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662891 | 0.77 | GAA (0.43) | ADCY2CHRM1KMT2AMEN1MAPT | |
| SCHEMBL8663372 | 0.77 | ALDH1A1 (0.44) | ADCY2CHRM1KMT2AMEN1MAPT | |
| SCHEMBL8662875 | 0.73 | GAA (0.40) | ADCY2CHRM1KMT2AMEN1MAPT | |
| SCHEMBL8663213 | 0.73 | GAA (0.40) | ADCY2CHRM1KMT2AMEN1MAPT | |
| SCHEMBL8528545 | 0.72 | MEN1 (0.42) | ADCY2CHRM1KMT2AMEN1ALDH1A1 | |
| SCHEMBL13879419 | 0.72 | AR (0.62) | ADCY2ARKMT2AMEN1MAPT | |
| SCHEMBL13879433 | 0.71 | AR (0.60) | ARKMT2AMEN1MAPTLMNA | |
| SCHEMBL6169375 | 0.70 | GAA (0.50) | ADCY2ARKMT2AMEN1MAPT | |
| SCHEMBL8711085 | 0.69 | KMT2A (0.51) | ADCY2CHRM1KMT2AMEN1MAPT | |
| SCHEMBL11501249 | 0.69 | HTT (0.43) | KMT2AOPRK1PDE4DLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876355-A1 | 2-THIOXO-IMIDAZOLIDIN-4-ONE DERIVATIVES AND THEIR USE FOR INCREASING HDL CHOLESTEROL CONCENTRATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-11-11 | — | — | EP | claimed |
| WO-1997019932-A1 | 2-THIOXO-IMIDAZOLIDIN-4-ONE DERIVATIVES AND THEIR USE FOR INCREASING HDL CHOLESTEROL CONCENTRATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-06-05 | — | — | WO | claimed |