Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663231 | 0.91 | ALDH1A1 (0.40) | GAAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL8662891 | 0.85 | GAA (0.43) | GAAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL8663213 | 0.81 | GAA (0.40) | GAAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL8663372 | 0.75 | ALDH1A1 (0.44) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8660438 | 0.73 | ADCY2 (0.47) | MEN1KMT2AMAPTALDH1A1ADCY2 | |
| SCHEMBL8528545 | 0.71 | MEN1 (0.42) | GAAMEN1KMT2AALDH1A1ADCY2 | |
| SCHEMBL6097864 | 0.69 | MEN1 (0.40) | MEN1KMT2AMAPTALDH1A1HCAR1 | |
| SCHEMBL8915515 | 0.68 | KMT2A (0.59) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8661557 | 0.67 | GAA (0.44) | GAAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL8663642 | 0.65 | GAA (0.46) | GAAMEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876355-A1 | 2-THIOXO-IMIDAZOLIDIN-4-ONE DERIVATIVES AND THEIR USE FOR INCREASING HDL CHOLESTEROL CONCENTRATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-11-11 | — | — | EP | claimed |
| WO-1997019932-A1 | 2-THIOXO-IMIDAZOLIDIN-4-ONE DERIVATIVES AND THEIR USE FOR INCREASING HDL CHOLESTEROL CONCENTRATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-06-05 | — | — | WO | claimed |