Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526108 | 0.90 | ALDH1A1 (0.42) | CHRM1ALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL8662891 | 0.80 | GAA (0.43) | MEN1KMT2ACHRM1HCAR1NPSR1 | |
| SCHEMBL8528166 | 0.76 | P2RX7 (0.37) | MEN1KMT2AHTR2B | |
| SCHEMBL8525857 | 0.75 | HTR2B (0.40) | MEN1KMT2AALDH1A1GAAHTR2C | |
| SCHEMBL8525685 | 0.73 | MGLL (0.41) | MEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL8660438 | 0.72 | ADCY2 (0.47) | MEN1KMT2ACHRM1ALDH1A1ADCY2 | |
| SCHEMBL8663372 | 0.72 | ALDH1A1 (0.44) | MEN1KMT2ACHRM1HCAR1NPSR1 | |
| SCHEMBL10569901 | 0.71 | MEN1 (0.52) | MEN1KMT2ANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10568509 | 0.71 | MEN1 (0.52) | MEN1KMT2ANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10567615 | 0.71 | MEN1 (0.52) | MEN1KMT2ANPSR1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885197-A1 | 2-THIOXOTETRAHYDROPYRIMIDIN-4-ONE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997032855-A1 | 2-THIOXOTETRAHYDROPYRIMIDIN-4-ONE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-09-12 | — | — | WO | disclosed |