Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30771240 | 0.88 | DRD2 (0.47) | SYKKMT2ACTSKNPSR1ATM | |
| SCHEMBL8659855 | 0.85 | SYK (0.40) | PPARAPPARGPPARDSYKSLC6A3 | |
| SCHEMBL8661115 | 0.85 | SYK (0.40) | PPARAPPARGPPARDSYKSLC6A3 | |
| SCHEMBL7269716 | 0.81 | SYK (0.47) | PPARAPPARGSYKKMT2ASERPINE1 | |
| SCHEMBL2942816 | 0.81 | SYK (0.47) | PPARAPPARGSYKKMT2ASERPINE1 | |
| SCHEMBL8662472 | 0.81 | KMT2A (0.48) | PPARAPPARGSYKSLC6A3MAPT | |
| SCHEMBL7348313 | 0.78 | CTSS (0.47) | SYKKMT2AEPHX2CTSKATM | |
| SCHEMBL8661789 | 0.78 | RAB9A (0.44) | SLC6A3MAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL266021 | 0.78 | CTSK (0.51) | PPARAPPARGSYKMAPTKMT2A | |
| SCHEMBL118384 | 0.78 | CTSK (0.51) | PPARAPPARGSYKMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760251-A | Taxol process and compounds | SEPRACOR, INC. (US) | 1998-06-02 | — | — | US | disclosed |
| WO-1997007110-A1 | PROCESS FOR PRODUCING TAXOL DERIVATIVES AND INTERMEDIATES THEREFOR | SEPRACOR, INC. (US) | 1997-02-27 | — | — | WO | disclosed |