Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.52 |
| ▸ | PNLIP | P16233 | 5/20 | 0.44 |
| ▸ | PYGL | P06737 | 8/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PARG | Q86W56 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658813 | 0.92 | GCGR (0.45) | GCGRPNLIPCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9137470 | 0.91 | GCGR (0.56) | GCGRPNLIPPYGLNPSR1PARG | |
| SCHEMBL8663097 | 0.90 | GCGR (0.55) | GCGRPNLIPPYGLALDH1A1NPSR1 | |
| SCHEMBL9134173 | 0.88 | NPSR1 (0.40) | GCGRPNLIPPYGLNPSR1 | |
| SCHEMBL8664412 | 0.84 | GCGR (0.55) | GCGRPNLIPPYGLALDH1A1NPSR1 | |
| SCHEMBL10787570 | 0.84 | GCGR (0.53) | GCGRPNLIPPYGLALDH1A1 | |
| SCHEMBL8657237 | 0.84 | MEN1 (0.42) | GCGRPNLIPNPSR1 | |
| SCHEMBL8663069 | 0.83 | GCGR (0.56) | GCGRPNLIPPYGLALDH1A1NPSR1 | |
| SCHEMBL8661087 | 0.83 | PYGL (0.49) | GCGRPYGLALDH1A1 | |
| SCHEMBL10495917 | 0.82 | PNLIP (0.48) | GCGRPNLIPPYGLALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| US-4602109-A | Novel pesticidal phenoxyphenyl and phenoxypyridyl benzoyl ureas and process for preparation | UNION CARBIDE CORPORATION (US) | 1986-07-22 | — | — | US | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |
| US-4540578-A | Pesticidal phenoxypyridyl benzoyl ureas | UNION CARBIDE CORPORATION (US) | 1985-09-10 | — | — | US | disclosed |
| EP-0113247-A1 | Pesticidal phenoxyphenyl and phenoxypyridyl benzoyl ureas and process for their preparation | UNION CARBIDE CORPORATION (US) | 1984-07-11 | — | — | EP | disclosed |