Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.33 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658622 | 0.79 | TSHR (0.40) | SMN1; SMN2PTGS2PTGS1PTGESCYP3A4 | |
| SCHEMBL8673510 | 0.73 | KMT2A (0.42) | NPC1RAB9ATSHRMAPK14L3MBTL1 | |
| SCHEMBL758276 | 0.72 | RAB9A (0.37) | NPC1RAB9ASMN1; SMN2PTGS2PTGS1 | |
| SCHEMBL13875590 | 0.66 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2CYP3A4ALOX15 | |
| SCHEMBL574076 | 0.65 | RAB9A (0.42) | NPC1RAB9APTGS2PTGS1ADORA2A | |
| SCHEMBL14561938 | 0.64 | PTGS2 (0.55) | NPC1RAB9APTGS2PTGS1PTGES | |
| SCHEMBL18986024 | 0.64 | PTGS2 (0.52) | NPC1RAB9APTGS2PTGS1PTGES | |
| SCHEMBL3279759 | 0.63 | KDM4E (0.42) | NPC1RAB9APTGS2PTGS1ADORA2A | |
| SCHEMBL15750991 | 0.63 | TRPV3 (0.47) | NPC1RAB9APTGS2PTGS1ADORA2A | |
| SCHEMBL9082652 | 0.63 | PRMT6 (0.49) | NPC1RAB9ASMN1; SMN2PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863879-A1 | HERBICIDAL SUBSTITUTED PYRAZOLE COMPOUNDS | ZENECA LIMITED (GB) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997018196-A1 | HERBICIDAL SUBSTITUTED PYRAZOLE COMPOUNDS | ZENECA LIMITED (GB) | 1997-05-22 | — | — | WO | disclosed |