SCHEMBL758276

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12359808	0.82	KDM4E (0.47)	KDM4ELMNAMAPTPOLB
	SCHEMBL758413	0.74	LMNA (0.38)	ALDH1A1PDE4BLMNAHPGD
	SCHEMBL16487838	0.74	PTGS1 (0.51)	RAB9APTGS1NPC1PTGS2KMT2A
	SCHEMBL365942	0.72	RAB9A (0.40)	RAB9APTGS1NPC1PTGS2KMT2A
	SCHEMBL3279759	0.72	KDM4E (0.42)	RAB9APTGS1NPC1PTGS2KMT2A
	SCHEMBL2611106	0.72	PKM (0.45)	RAB9APTGS1NPC1PTGS2KMT2A
	SCHEMBL938217	0.72	RAB9A (0.40)	RAB9APTGS1NPC1PTGS2KMT2A
	SCHEMBL8662387	0.72	NPC1 (0.42)	RAB9APTGS1NPC1PTGS2ALOX5
	SCHEMBL1463361	0.71	HDAC3 (0.41)	RAB9APTGS1NPC1PTGS2KMT2A
	SCHEMBL16705384	0.71	RAB9A (0.42)	RAB9APTGS1NPC1PTGS2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.