Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 4/20 | 0.33 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662486 | 0.92 | MTNR1B (0.40) | MTNR1BBCHEACHEMAPTMEN1 | |
| SCHEMBL6858153 | 0.86 | ITGA4 (0.38) | MEN1KMT2A | |
| SCHEMBL26302681 | 0.85 | SLC6A11 (0.42) | MTNR1BMAPTMEN1KMT2A | |
| SCHEMBL14978147 | 0.85 | SLC6A11 (0.42) | MTNR1BMAPTMEN1KMT2A | |
| SCHEMBL26302685 | 0.85 | SLC6A11 (0.42) | MTNR1BMAPTMEN1KMT2A | |
| SCHEMBL9908638 | 0.85 | SLC6A11 (0.42) | MTNR1BMAPTMEN1KMT2A | |
| SCHEMBL26302691 | 0.85 | SLC6A11 (0.42) | MTNR1BMAPTMEN1KMT2A | |
| SCHEMBL8660379 | 0.85 | SLC6A1 (0.34) | MTNR1BMEN1KMT2A | |
| SCHEMBL8661457 | 0.84 | HPGD (0.35) | — | |
| SCHEMBL9908645 | 0.84 | SLC6A11 (0.42) | MTNR1BMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714606-A | OLIGONUCLEOTIDE HAVING RECEPTOR BINDING SITES; ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS, MEDICAL DIAGNOSIS | ISIS PHARMACEUTICALS, INC. (US) | 1998-02-03 | — | — | US | disclosed |
| EP-0739335-A4 | PYRROLIDINE-CONTAINING MONOMERS AND OLIGOMERS | ISIS PHARMACEUTICALS INC (US) | 1997-04-02 | — | — | EP | disclosed |
| EP-0739335-A1 | PYRROLIDINE-CONTAINING MONOMERS AND OLIGOMERS | ISIS PHARMACEUTICALS, INC. (US) | 1996-10-30 | — | — | EP | disclosed |
| US-5510476-A | SOLID PHASE SYNTHESIS USING AN ACIDIC SOLUTION OF THE SCAVENGER TO DEPROTECT THE 5'-HYDROXY AND NEUTRALIZE THE CARBO ANION RELEASED; HIGH YIELDS | ISIS PHARMACEUTICALS, INC. (US) | 1996-04-23 | — | — | US | disclosed |
| WO-1995018792-A1 | PYRROLIDINE-CONTAINING MONOMERS AND OLIGOMERS | ISIS PHARMACEUTICALS, INC. (US) | 1995-07-13 | — | — | WO | disclosed |