SCHEMBL866304

SCHEMBL866304

Nc1c(-c2ccccc2)cc(-c2c(-c3ccccc3)cc(-c3ccccc3)c(N)c2-c2ccccc2)cc1-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.40
ALDH1A1 P00352 2/20 0.40
IKBKB O14920 3/20 0.37
CHUK O15111 3/20 0.37
IKBKE Q14164 1/20 0.37
PKMYT1 Q99640 1/20 0.37
SMARCA2 P51531 1/20 0.37
SMARCA4 P51532 1/20 0.37
PBRM1 Q86U86 1/20 0.37
BACE1 P56817 1/20 0.37
MAPT P10636 3/20 0.35
MAOA P21397 1/20 0.34
MAPK1 P28482 2/20 0.34
USP7 Q93009 1/20 0.34
MAP4K4 O95819 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
USP2 O75604 1/20 0.34
ESR1 P03372 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21278695 0.94 HSD17B10 (0.44) HSD17B10ALDH1A1IKBKBCHUKIKBKE
Hydrochloric Acid SCHEMBL28480643 0.92 HSD17B10 (0.43) HSD17B10ALDH1A1IKBKBCHUKIKBKE
SCHEMBL173475 0.86 HSD17B10 (0.52) HSD17B10ALDH1A1SMARCA2SMARCA4PBRM1
SCHEMBL30776965 0.84 ALDH1A1 (0.45) HSD17B10ALDH1A1IKBKBCHUKIKBKE
SCHEMBL30594444 0.81 HSD17B10 (0.44) HSD17B10ALDH1A1IKBKBCHUKIKBKE
SCHEMBL21046679 0.81 HSD17B10 (0.44) HSD17B10ALDH1A1IKBKBCHUKIKBKE
SCHEMBL5016738 0.80 HSD17B10 (0.52) HSD17B10ALDH1A1IKBKBCHUKIKBKE
SCHEMBL530448 0.79 HSD17B10 (0.48) HSD17B10ALDH1A1IKBKBCHUKIKBKE
SCHEMBL6003324 0.79 HSD17B10 (0.48) HSD17B10ALDH1A1SMARCA2SMARCA4PBRM1
SCHEMBL20721640 0.79 ALDH1A1 (0.44) HSD17B10ALDH1A1IKBKBCHUKIKBKE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250180952-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2025-06-05 US disclosed
EP-4493638-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2025-01-22 EP disclosed
CN-118871548-A Photoalignment materials 罗利克技术有限公司 2024-10-29 CN disclosed
CN-118027412-A Photo-alignment material 罗利克技术有限公司 2024-05-14 CN disclosed
WO-2023174773-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2023-09-21 WO disclosed
US-11634544-B2 Photoaligning materials Rolic Technologies AG (CH) 2023-04-25 US disclosed
US-20210340330-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2021-11-04 US disclosed
CN-108912011-B Photoalignment material 罗立克科技股份公司 2021-09-24 CN disclosed
US-20200377647-A1 RESIN COMPOSITION, RESIN SHEET, CURED RESIN PRODUCT, RESIN SUBSTRATE, AND LAMINATE SUBSTRATE TDK CORPORATION (JP) 2020-12-03 US disclosed
US-20200377647-A1 RESIN COMPOSITION, RESIN SHEET, CURED RESIN PRODUCT, RESIN SUBSTRATE, AND LAMINATE SUBSTRATE TDK CORPORATION (JP) 2020-12-03 US disclosed
US-20100266814-A1 PHOTOALIGNMENT COMPOSITION ROLIC AG (CH) 2010-10-21 US disclosed
EP-2222815-A1 PHOTOALIGNMENT COMPOSITION Rolic Ltd. (CH) 2010-09-01 EP disclosed
US-20100048849-A1 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP ROLIC AG (CH) 2010-02-25 US disclosed
EP-2152660-A2 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP Rolic AG (CH) 2010-02-17 EP disclosed
WO-2009080271-A1 PHOTOALIGNMENT COMPOSITION ROLIC LTD. (CH) 2009-07-02 WO disclosed
WO-2008145225-A2 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP ROLIC AG (CH) 2008-12-04 WO disclosed
US-20080293888-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-11-27 US disclosed
EP-1966119-A1 PHOTOCROSSLINKABLE MATERIALS Rolic AG (CH) 2008-09-10 EP disclosed
WO-2007071091-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2007-06-28 WO disclosed
US-5177176-A Soluble pseudo rod-like polyimides having low coefficient of thermal expansion E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048849-A1 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP DDC, ALAD, DYNC1LI1 HSD17B10 2069/4885ALDH1A1 97/4885IKBKB 1740/4885
US-20080293888-A1 Photocrosslinkable Materials DDC, PARG, ALAD HSD17B10 2394/4885ALDH1A1 313/4885IKBKB 2106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.