Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658809 | 0.96 | KDM4E (0.43) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL8659453 | 0.92 | ALDH1A1 (0.36) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL8659385 | 0.91 | TAS1R3 (0.40) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL8662513 | 0.87 | MEN1 (0.45) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL8659984 | 0.86 | KDR (0.42) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL8658919 | 0.85 | PYGL (0.41) | NPC1ARTDP1POLB | |
| SCHEMBL8656628 | 0.85 | MEN1 (0.45) | MEN1KMT2AKDM4EMAPTUSP2 | |
| SCHEMBL8662606 | 0.85 | S1PR3 (0.41) | MEN1KMT2ANPC1ARPOLB | |
| SCHEMBL9135451 | 0.84 | MEN1 (0.41) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL10639537 | 0.82 | NPC1 (0.45) | MEN1KMT2AKDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0115210-B1 | PESTICIDAL BENZOYL UREAS AND PROCESS FOR THEIR PREPARATION | UNION CARBIDE CORPORATION (US) | 1988-05-11 | — | — | EP | disclosed |
| US-4659724-A | Certain 1-[4-(5-cyano-2-pyridyloxy)phenyl-benzoyl ureas having pesticidal properties | UNION CARBIDE CORPORATION (US) | 1987-04-21 | — | — | US | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |
| EP-0115210-A1 | Pesticidal benzoyl ureas and process for their preparation | UNION CARBIDE CORPORATION (US) | 1984-08-08 | — | — | EP | disclosed |