Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664293 | 0.91 | KMT2A (0.48) | RAB9ANPC1SMN1; SMN2POLBHTT | |
| SCHEMBL9230727 | 0.89 | CASP3 (0.49) | RAB9ASMN1; SMN2HTTKMT2AMAPT | |
| SCHEMBL9004670 | 0.87 | MAPT (0.55) | RAB9ANPC1SMN1; SMN2POLBHTT | |
| SCHEMBL8667225 | 0.82 | LMNA (0.49) | RAB9ANPC1SMN1; SMN2HTTKMT2A | |
| SCHEMBL9004777 | 0.76 | KMT2A (0.51) | RAB9ANPC1SMN1; SMN2POLBHTT | |
| SCHEMBL9004624 | 0.75 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2POLBKMT2A | |
| SCHEMBL8667830 | 0.75 | SENP6 (0.61) | RAB9ANPC1SMN1; SMN2POLBKMT2A | |
| SCHEMBL8664300 | 0.74 | SMN1; SMN2 (0.50) | RAB9ANPC1SMN1; SMN2POLBHTT | |
| SCHEMBL9004724 | 0.74 | EPHX2 (0.57) | RAB9ANPC1SMN1; SMN2HTTKMT2A | |
| SCHEMBL9004678 | 0.73 | SMN1; SMN2 (0.51) | RAB9ANPC1SMN1; SMN2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646574-B1 | Ketonic indane derivatives, their preparation and therapeutic application thereof | INNOTHERA LAB SA (FR) | 1998-12-09 | — | — | EP | disclosed |
| EP-0646574-A1 | Ketonic indane derivatives, their preparation and therapeutic application thereof | LABORATOIRE INNOTHERA Société Anonyme (FR) | 1995-04-05 | — | — | EP | disclosed |