Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | JAK1 | P23458 | 2/20 | 0.47 |
| ▸ | TYK2 | P29597 | 2/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664293 | 0.90 | KMT2A (0.48) | CASP3SENP8SENP7SENP6HTT | |
| SCHEMBL8663571 | 0.89 | RAB9A (0.45) | CASP3SENP8SENP7SENP6HTT | |
| SCHEMBL8667225 | 0.89 | LMNA (0.49) | CASP3SENP8SENP7SENP6HTT | |
| SCHEMBL9004758 | 0.84 | SENP6 (0.67) | CASP3SENP8SENP7SENP6HTT | |
| SCHEMBL9231193 | 0.81 | SMN1; SMN2 (0.47) | CASP3SENP8SENP7SENP6HTT | |
| SCHEMBL9232985 | 0.78 | KMT2A (0.52) | CASP3SENP8SENP7SENP6HTT | |
| SCHEMBL9004670 | 0.75 | MAPT (0.55) | CASP3SENP8SENP7SENP6HTT | |
| SCHEMBL9004777 | 0.75 | KMT2A (0.51) | CASP3SENP8SENP7SENP6HTT | |
| SCHEMBL8667830 | 0.74 | SENP6 (0.61) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL9240114 | 0.73 | CASP3 (0.56) | CASP3SENP8SENP7SENP6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646574-A1 | Ketonic indane derivatives, their preparation and therapeutic application thereof | LABORATOIRE INNOTHERA Société Anonyme (FR) | 1995-04-05 | — | — | EP | disclosed |