Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 12/20 | 0.46 |
| ▸ | MMP1 | P03956 | 9/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 6/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650547 | 0.89 | L3MBTL1 (0.40) | MMP3MMP1L3MBTL1MMP2 | |
| SCHEMBL8665728 | 0.88 | MMP3 (0.44) | MMP3MMP1MMP2 | |
| SCHEMBL8665565 | 0.88 | MMP3 (0.56) | MMP3MMP1MMP2TNFMMP13 | |
| SCHEMBL6417772 | 0.80 | MMP3 (0.48) | MMP3MMP1MMP2TNFMMP13 | |
| SCHEMBL7764984 | 0.80 | MMP3 (0.48) | MMP3MMP1MMP2TNFMMP13 | |
| SCHEMBL8668754 | 0.78 | MMP3 (0.58) | MMP3MMP1MMP2TNFMMP13 | |
| SCHEMBL6412000 | 0.78 | FCER2 (0.44) | MMP3MMP1MMP2 | |
| SCHEMBL8667836 | 0.77 | FCER2 (0.48) | MMP3MMP1MMP2 | |
| SCHEMBL8652782 | 0.77 | CYP2C9 (0.43) | MMP3MMP1MMP2 | |
| SCHEMBL8664100 | 0.77 | MMP2 (0.49) | MMP3MMP1MMP2TNFADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712390-B1 | SUCCINAMIDE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS GELATINASE AND COLLAGENASE INHIBITORS | CELLTECH THERAPEUTICS LTD (GB) | 1998-12-09 | — | — | EP | disclosed |