Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.30 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670561 | 0.89 | DDR1 (0.35) | SMN1; SMN2SETDB1LMNAALDH1A1BRD9 | |
| SCHEMBL8666669 | 0.84 | SETDB1 (0.36) | SMN1; SMN2SETDB1 | |
| SCHEMBL8663188 | 0.81 | ALDH1A1 (0.42) | SMN1; SMN2SETDB1LMNATP53MEN1 | |
| SCHEMBL8664609 | 0.81 | SETDB1 (0.37) | SMN1; SMN2SETDB1LMNAMAPTTP53 | |
| SCHEMBL8660658 | 0.69 | SETDB1 (0.39) | SMN1; SMN2SETDB1LMNAMAPTBRD9 | |
| SCHEMBL6301740 | 0.69 | KDM4A (0.38) | SMN1; SMN2LMNAMAPTALDH1A1POLB | |
| SCHEMBL5643020 | 0.68 | TAAR1 (0.44) | MEN1ALDH1A1POLBKMT2ATDP1 | |
| SCHEMBL8675983 | 0.67 | SETDB1 (0.38) | SMN1; SMN2SETDB1LMNAALDH1A1BRD9 | |
| SCHEMBL17212275 | 0.66 | FFAR4 (0.42) | SMN1; SMN2LMNAMAPTTP53ALDH1A1 | |
| SCHEMBL8155272 | 0.66 | NPC1 (0.34) | SMN1; SMN2SETDB1LMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874831-A1 | PROCESSES AND COMPOUNDS FOR PREPARING CYCLIC UREA FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997019935-A1 | PROCESSES AND COMPOUNDS FOR PREPARING CYCLIC UREA FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-06-05 | — | — | WO | disclosed |